TXNRD1 Polyclonal Antibody, Cy3 Conjugated

Product Specifications

Background

Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.

Synonyms

TR; TR1; TXNR; TRXR1; GRIM-12; Thioredoxin reductase 1, cytoplasmic; Gene associated with retinoic and interferon-induced mortality 12 protein; Gene associated with retinoic and IFN-induced mortality 12 protein; KM-12-derived reductase-like factor; Thioredoxin reductase TR1; TXNRD1; GRIM12; KDRF

Gene ID

7296

Swiss Prot

Q16881

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

451-550/649

Target

TXNRD1

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human TXNRD1

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

1µg/µl

Dilution

WB (WB=1:500-2000), IF (IF=1:50-200), Flow-Cyt (Flow-Cyt=1:20-50)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

7296

Predicted Cross Reactivity

Dog, Cow, Pig, Horse

Available Sizes

Curated Selection

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