TXNRD1 Polyclonal Antibody

Product Specifications

Background

Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.

Synonyms

TR; TR1; TXNR; TRXR1; GRIM-12; Thioredoxin reductase 1, cytoplasmic; Gene associated with retinoic and interferon-induced mortality 12 protein; Gene associated with retinoic and IFN-induced mortality 12 protein; KM-12-derived reductase-like factor; Thioredoxin reductase TR1; TXNRD1; GRIM12; KDRF

Gene ID

7296

Swiss Prot

Q16881

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

451-550/649

Target

TXNRD1

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human TXNRD1

Applications

WB, IHC-P, IHC-F, IP, IF, Flow-Cyt, ICC/IF

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (WB=1:500-2000), IHC-P (IHC-P=1:50-200), IHC-F (IHC-F=1:50-200), IP (IP=1:20-50), IF (IF=1:50-200), Flow-Cyt (Flow-Cyt=1:20-50), ICC/IF (ICC/IF=1:50-200)