DCUN1D4 Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
The DCN1-like protein family is comprised of Dcun1D1, Dcun1D2, Dcun1D3, Dcun1D4 and Dcun1D5. The founding member, Dcun1D1, is involved in the malignant transformation of squamous cell lineage.Dcun1D4, (defective in cullin neddylation protein 1-like protein 4 or DCN1-like protein 4), also designated KIAA0276, exists as 2 isoforms as a result of alternative splicing and contains one DCUN1 domain. The gene encoding Dcun1D4 maps to chromosome 4, which houses nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
Synonyms
DCN1, defective in cullin neddylation 1, domain containing 4; DCN1 like protein 4; DCUN1 domain containing protein 4; DCUN1D 4; KIAA0276; DCNL4_HUMAN.
Gene ID
23142
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
161-270/292
Target
DCUN1D4
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human DCUN1D4
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
23142
Predicted Cross Reactivity
Human, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken
Curated Selection
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