Pamabrom
Pamabrom is a diuretic that acts on the opioid receptor-nitric oxide (NO) -cyclic guanosine monophosphate (cGMP) -K+ channel pathway. Pamabrom exerts peripheral antinociceptive activity by activating this pathway. The mechanism involves activating opioid receptors, promoting the release of nitric oxide, and then influencing cyclic guanosine monophosphate and K channels to produce an analgesic effect. Pamabrom is orally active and is mainly used in the research and treatment of premenstrual syndrome and primary dysmenorrhea[1].
Product Specifications
CAS Number
606-04-2
UNSPSC
12352005
Hazard Statement
H302
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/pamabrom.html
Purity
99.92
Solubility
DMSO : 150 mg/mL (ultrasonic)
Smiles
O=C(N1C)N(C)C2=C(N=C(Br)N2)C1=O.CC(C)(N)CO
Molecular Formula
C11H18BrN5O3
Molecular Weight
348.20
Precautions
H302
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Frequently Asked Questions
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