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CCDC34 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC34 (coiled-coil domain containing 34), also known as Renal carcinoma antigen NY-REN-41, is a 373 amino acid protein that is expressed in testis, breast, lung, placenta, liver and small intestine. A translocation between the short arms of chromosomes 11 and 18 affecting the CCDC34 gene has been identified in a patient with hamartoma of the retinal pigment epithelium. There are two isoforms of CCDC34 that are produced as a result of alternative splicing events.

Synonyms

Ccdc34; Coiled coil domain containing protein 34; L15; RAMA3; Renal carcinoma antigen NY REN 41; CCD34_HUMAN.

Gene ID

91057

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Rat

Immunogen

177-280/373

Target

CCDC34

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human CCDC34

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

91057

Predicted Cross Reactivity

Human, Mouse, Sheep, Pig

Curated Selection

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