COMMD1 Polyclonal Antibody, Cy5 Conjugated
Product Specifications
Background
Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF-kappa-B activity. Down-regulates SOD1 activity by interfering with its homodimerization. Plays a role in copper ion homeostasis. Can bind one copper ion per monomer. May function to facilitate biliary copper excretion within hepatocytes.Tissue specificity:Ubiquitous. Highest expression in the liver, with lower expression in brain, lung, placenta, pancreas, small intestine, heart, skeletal muscle, kidney and placenta.
Synonyms
C2orf5; COMD1; COMD1_HUMAN; COMM domain-containing protein 1; COMMD1; copper metabolism domain containing 1; MGC27155; MURR1; Protein Murr1.
Gene ID
150684
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Immunogen
95-190/190
Target
COMMD1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy5
Source
KLH conjugated synthetic peptide derived from human COMMD1/MURR1
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
625,650nm/670nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
150684
Predicted Cross Reactivity
Rat, Cow, Sheep, Horse, Rabbit
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
042772-PE 200 µL
TFIP11, NT (TFIP11, STIP, Tuftelin-interacting protein 11, Septin and tuftelin-interacting protein 1) (PE) discontinued
Ask
View Details MBS6378503-01 0.1 mL
FGF19 (Fibroblast Growth Factor 19, FGF-19, UNQ334/PRO533) (PE)
Ask
View Details 
MBS6378503-02 5x 0.1 mL
FGF19 (Fibroblast Growth Factor 19, FGF-19, UNQ334/PRO533) (PE)
Ask
View Details 