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CNIH3 Polyclonal Antibody, Biotin Conjugated

Product Specifications

Background

CNIH2 and CNIH3 regulate the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs) . They promote their targeting to the cell membrane and synapses and modulate their gating properties by regulating their rates of activation, deactivation and desensitization. CNIH2 also blocks CACNG8-mediated resensitization of AMPA receptors.

Synonyms

Protein cornichon homolog 2; CNIH2; Cornichon family AMPA receptor auxiliary protein 2; Protein cornichon homolog 3; CNIH3; Cornichon family AMPA receptor auxiliary protein 3

Gene ID

254263; 149111

Swiss Prot

Q6PI25; Q8TBE1

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Rat

Immunogen

25-120/160

Target

CNIH3

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human CNIH2/CNIH3

Applications

WB, ELISA, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Specificity

This antibody detects both CNIH2 and CNIH3 proteins

Gene ID URL

254263; 149111

Predicted Cross Reactivity

Human, Mouse, Dog, Cow, Pig, Horse, Rabbit

Curated Selection

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