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Ensaculin

Ensaculin is an NMDA receptor channel blocker. Ensaculin has neuroprotective effects in NMDA toxicity models and promotes neuronal growth in primary cultures of rat brain cells. Ensaculin has the potential to be developed as an anti-dementia drug that acts on various neurotransmitter systems[1].

Product Specifications

Product Name Alternative

KA-672 (hydrochloride) ; Anseculin (hydrochloride)

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ensaculin.html

Smiles

O=C1C(C)=C(C)C2=CC(OCCCN3CCN(C4=CC=CC=C4OC)CC3)=C(OC)C=C2O1.[H]Cl

Molecular Formula

C26H33ClN2O5

Molecular Weight

489.00

References & Citations

[1]Hoerr R, et al. Ensaculin (KA-672 HCl) : a multitransmitter approach to dementia treatment. CNS Drug Rev. 2002 Summer;8 (2) :143-58.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-19225/Ensaculin-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-19225/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

CAS Number

[209969-60-8]

Curated Selection

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