Ensaculin
Ensaculin is an NMDA receptor channel blocker. Ensaculin has neuroprotective effects in NMDA toxicity models and promotes neuronal growth in primary cultures of rat brain cells. Ensaculin has the potential to be developed as an anti-dementia drug that acts on various neurotransmitter systems[1].
Product Specifications
CAS Number
209969-60-8
Product Name Alternative
KA-672 (hydrochloride) ; Anseculin (hydrochloride)
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ensaculin.html
Smiles
O=C1C(C)=C(C)C2=CC(OCCCN3CCN(C4=CC=CC=C4OC)CC3)=C(OC)C=C2O1.[H]Cl
Molecular Formula
C26H33ClN2O5
Molecular Weight
489.00
References & Citations
[1]Hoerr R, et al. Ensaculin (KA-672 HCl) : a multitransmitter approach to dementia treatment. CNS Drug Rev. 2002 Summer;8 (2) :143-58.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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