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Robo2 Polyclonal Antibody, PerCP Conjugated

Product Specifications

Background

Receptor for SLIT2, and probably SLIT1, which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development.Involvement in disease:Defects in ROBO2 are the cause of vesicoureteral reflux type 2 (VUR2) . VUR is a complex, genetically heterogeneous developmental disorder characterized by the retrograde flow of urine from the bladder into the ureter and is associated with reflux nephropathy, the cause of 15% of end-stage renal disease in children and young adults.

Synonyms

Lea; Robo 2; ROBO2; ROBO2_HUMAN; Roundabout 2; Roundabout homolog 2; roundabout, axon guidance receptor, homolog 2 Drosophila; Roundabout2; SAX 3; SAX3.

Gene ID

6092

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

144-220/1378

Target

Robo2

Clonality

Polyclonal

Isotype

IgG

Conjugation

PerCP

Source

KLH conjugated synthetic peptide derived from human Robo2

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

482nm/677nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

6092

Predicted Cross Reactivity

Human, Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit

Curated Selection

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