CLK2 Polyclonal Antibody

Product Specifications

Background

CDC-like kinase 2 (CLK2) belongs to a family of autophosphorylating kinases termed CLK (CDC2/CDC28-like kinases), which have been shown to phosphorylate serine- and arginine-rich (SR) proteins of the spliceosomal complex, and to influence alternative splicing in overexpression systems. Recent findings demonstrated that the CLK kinases activate PTP-1B family members, and this phosphatase may be an important cellular target for CLK action. Mutations in the CLK2 proteins affect organismal features such as development, behavior, reproduction, and aging as well as cellular features such as the cell cycle, apoptosis, the DNA replication checkpoint, and telomere length.

Synonyms

CDC like kinase 2; CLK 2; CLK kinase; Clk2 Scamp3; Dual specicity protein kinase CLK2; hCLK 2; hCLK2; MGC61500; Tu52; CLK2_HUMAN.

Gene ID

1196

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

401-499/499

Target

CLK2

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human CLK2

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

1196

Predicted Cross Reactivity

Dog, Cow, Pig, Horse, Chicken, Rabbit

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

GA212377 1 Kit

Mouse Mbd6 activation kit by CRISPRa

Ask

View Details

MBS9339341 Inquire

Chicken Contactin-associated protein-like 5, CNTNAP5 ELISA Kit

Ask

View Details

bsm-62041R-BF555 100 µL

ACRV1 Recombinant Antibody, AbBy Fluor™ 555 Conjugated

Ask

View Details

STD#3108 1.2 mL

Pribolab® Deoxynivalenol-15-Glucuronide (25 µg/mL) in Methanol

Ask

View Details

MP215600 200 Reactions

Sumo2 Mouse qPCR Primer Pair (NM_133354)

Ask

View Details

abx979215-01 150 µg

Mouse KLF7 shRNA Plasmid

Ask

View Details