CCNDBP1 Polyclonal Antibody, Cy5.5 Conjugated
Product Specifications
Background
May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.Tissue specificity: Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.
Synonyms
Maternal inhibition of dferentiation; SECC 8; SSEC 8; CCDB1_HUMAN; CCNDBP 1; Ccndbp1; Cyclin D type binding protein 1; Cyclin-D1-binding protein 1; D type cyclin interacting protein 1; DIP 1; DIP1; GCIP; Grap 2 and cyclin D interacting protein; Grap 2 cyclin D interacting protein GCIP; Grap 2 cyclin interacting protein; Grap2 and cyclin D interacting protein; Grap2 and cyclin-D-interacting protein; Grap2 cyclin D interacting protein GCIP; Grap2 cyclin interacting protein; HHM protein; Human homolog of Maid; MAID; MAID protein; Stage specic embryonic cDNA 8.
Gene ID
23582
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Immunogen
281-360/360
Target
CCNDBP1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy5.5
Source
KLH conjugated synthetic peptide derived from human CCNDBP1
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
675nm/694nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
23582
Predicted Cross Reactivity
Human, Mouse, Rat, Cow, Sheep, Pig, Horse, Rabbit
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
