GPSM1 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G (i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.
Synonyms
Activator of G-protein signaling 3; AGS3; AGS3 homolog; C10a; G protein signaling modulator 1 AGS3 like, C. elegans; G-protein-signaling modulator 1; GPSM1; GPSM1_HUMAN.
Gene ID
26086
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Immunogen
201-300/675
Target
GPSM1
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from human GPSM1
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
26086
Predicted Cross Reactivity
Human, Mouse, Rat, Sheep, Horse
Curated Selection
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