SKA1 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the interaction with microtubules.
Synonyms
Ska1; SKA1_HUMAN; Spindle and kinetochore associated complex subunit 1; Spindle and kinetochore associated protein 1; Spindle and kinetochore-associated protein 1; Spindle and KT kinetochore associated 1; Spindle and KT associated 1; C18orf24; MGC10200.
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Immunogen
181-255/255
Target
SKA1
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from human SKA1
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
168665-AF-FITC 100 µL
CD11c (CD11 antigen-like family member C, Complement component 3 receptor 4 subunit, Integrin alpha-X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), Leu M5 alpha subunit, Leukocyte adhesion glycoprotein p150 95 alpha chain, Myeloid membrane antigen alpha subunit, p150/95) (FITC)
Ask
View Details 
