KIFC1 Polyclonal Antibody, APC Conjugated
Product Specifications
Background
The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIFC1 is a 673 amino acid protein that belongs to the kinesin-like family of proteins. KIFC1 localizes to the nucleus and contains a C-terminal kinesin-motor domain. Functioning as a minus-end directed microtubule-dependent motor, KIFC1 works together with NuMA and cytoplasmic Dynein to organize microtubule minus ends at spindle poles. HeLa cells deficient in KIFC1 exhibit multipolar mitotic spindles, suggesting that KIFC1 is essential for bipolar spindle formation.
Synonyms
HSET KNSL2; K C1; KC 1; KC1; KC1_HUMAN; Kinesin family member C1; Kinesin like 2; Kinesin like protein 2; Kinesin like protein KC1; Kinesin related protein HSET; Kinesin-like protein 2; Kinesin-like protein KC1; Kinesin-related protein HSET; KNSL 2; KNSL2; Mitotic kinesin like protein 2; MKLP 2
Gene ID
3833
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat, Bovine, Pig
Target
KIFC1
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human KIFC1
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
WB (WB=1:500-2000), IF (IF=1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3833
Curated Selection
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