Renalase Polyclonal Antibody, PE Conjugated

Product Specifications

Background

Catalyzes the oxidation of the less abundant alpha-NAD (P) H isoform to form beta-NAD (P) (+) . The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.

Synonyms

C10orf59; RENALASE; Monoamine oxidase-C; MAO-C; alpha-NAD (P) H oxidase/anomerase; RNLS

Gene ID

55328

Swiss Prot

Q5VYX0

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Human, Mouse

Immunogen

201-300/342

Target

Renalase

Clonality

Polyclonal

Isotype

IgG

Conjugation

Source

KLH conjugated synthetic peptide derived from human Renalase

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

55328

Predicted Cross Reactivity

Rat, Dog, Pig, Horse, Rabbit

Available Sizes

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