Renalase Polyclonal Antibody, APC Conjugated
Product Specifications
Background
Catalyzes the oxidation of the less abundant alpha-NAD (P) H isoform to form beta-NAD (P) (+) . The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.
Synonyms
C10orf59; RENALASE; Monoamine oxidase-C; MAO-C; alpha-NAD (P) H oxidase/anomerase; RNLS
Gene ID
55328
Swiss Prot
Q5VYX0
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Human, Mouse
Immunogen
201-300/342
Target
Renalase
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human Renalase
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
55328
Predicted Cross Reactivity
Rat, Dog, Pig, Horse, Rabbit
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