Corin Polyclonal Antibody, AbBy Fluor™ 405 Conjugated
Product Specifications
Background
Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. Isoform 2: has weaker endopeptidase activity compared to isoform 1.
Synonyms
CRN; ATC2; Lrp4; PEE5; TMPRSS10; Atrial natriuretic peptide-converting enzyme; Corin; Heart-specific serine proteinase ATC2; Pro-ANP-converting enzyme; Transmembrane protease serine 10
Gene ID
10699
Swiss Prot
Q9Y5Q5
Cellular Locus
Secreted, Cell membrane
Host
Rabbit
Cross Reactivity
Human
Immunogen
165-245/1042
Target
Corin
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 405
Source
KLH conjugated synthetic peptide derived from human Corin
Applications
IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
401nm/421nm
Concentration
1µg/µl
Dilution
IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
10699
Predicted Cross Reactivity
Mouse, Rat, Dog, Pig, Horse
More Discoveries
Explore Other Products
Browse additional items from our catalog
RC224959L4V 200 µL
Phosphatidic acid phosphatase type 2B (PLPP3) (NM_177414) Human Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details 
