NUP50 Polyclonal Antibody, PE Conjugated

Product Specifications

Background

Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling. Interacts with multiple transport receptor proteins including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B.

Synonyms

NPAP60; NPAP60L; Nuclear pore complex protein Nup50; 50 kDa nucleoporin; Nuclear pore-associated protein 60 kDa-like; Nucleoporin Nup50; NUP50; PRO1146

Gene ID

10762

Swiss Prot

Q9UKX7

Cellular Locus

Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Rat

Immunogen

351-450/468

Target

NUP50

Clonality

Polyclonal

Isotype

IgG

Conjugation

Source

KLH conjugated synthetic peptide derived from human NUP50

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

10762

Predicted Cross Reactivity

Human, Mouse, Dog, Pig, Horse, Rabbit

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