MDMX Polyclonal Antibody, Cy5 Conjugated

Product Specifications

Background

Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.

Synonyms

HDMX; MDMX; MRP1; Protein Mdm4; Double minute 4 protein; Mdm2-like p53-binding protein; Protein Mdmx; p53-binding protein Mdm4; MDM4

Gene ID

4194

Swiss Prot

O15151

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

301-400/490

Target

MDMX

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy5

Source

KLH conjugated synthetic peptide derived from human MDM4

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

625,650nm/670nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4194

Predicted Cross Reactivity

Human, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

M914-500G 500 g

Dextrose Tryptone Broth, Modified

Ask

View Details

NBP2-74639IR 0.1 mL

Mouse Monoclonal Troponin I Type 1 (slow skeletal) Antibody (OTI8H8) [DyLight 755]

Ask

View Details

MBS657040-01 1 mg

Tissue, Total Protein, Human Adult Normal, Heart, Pericardium

Ask

View Details

MBS657040-02 5x 1 mg

Tissue, Total Protein, Human Adult Normal, Heart, Pericardium

Ask

View Details

SI213542B 1 Each

Rat Sox15 Pre-designed siRNA Set B

Ask

View Details

LC413077 20 µg

COPRS (NM_018405) Human Over-expression Lysate

Ask

View Details