Phospho-TIRAP (Tyr86) Polyclonal Antibody, Cy3 Conjugated
Product Specifications
Background
Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.
Synonyms
Mal; wyatt; BACTS1; MyD88-2; Toll/interleukin-1 receptor domain-containing adapter protein; TIR domain-containing adapter protein; Adaptor protein Wyatt; MyD88 adapter-like protein; TIRAP
Gene ID
114609
Swiss Prot
P58753
Modification Site
Tyr86
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Rat
Target
Phospho-TIRAP (Tyr86)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy3
Source
KLH conjugated synthetic acetylpeptide derived from human TIRAP around phosphorylation site of Tyr86 [KD (p-Y) DV]
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
512,550nm/570,615nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
114609
Predicted Cross Reactivity
Mouse, Dog, Cow, Pig, Horse, GuineaPig
More Discoveries
Explore Other Products
Browse additional items from our catalog
RC216207L3 10 µg
P2X2 (P2RX2) (NM_170682) Human Tagged Lenti ORF Clone
Sign In for Pricing
View Details 
N2275-01A-ML405 100 µL
Newcastle Disease Virus (NDV) (MaxLight 405) discontinued
Sign In for Pricing
View Details JOT-EK4925Hu 96 wells
Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C,MGAT4C ELISA KIT
Sign In for Pricing
View Details ![Rabbit Polyclonal Lipin 1 Antibody [Alexa Fluor 532]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
NB110-57150AF532 0.1 mL
Rabbit Polyclonal Lipin 1 Antibody [Alexa Fluor 532]
Sign In for Pricing
View Details