GAS 6 Polyclonal Antibody, RBITC Conjugated
Product Specifications
Background
Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
Synonyms
AXSF; AXLLG; Growth arrest-specific protein 6; GAS-6; AXL receptor tyrosine kinase ligand; GAS6
Gene ID
2621
Swiss Prot
Q14393
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Human, Mouse
Immunogen
551-650/721
Target
GAS 6
Clonality
Polyclonal
Isotype
IgG
Conjugation
RBITC
Source
KLH conjugated synthetic peptide derived from human GAS 6
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
570nm/595nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
2621
Predicted Cross Reactivity
Rat, Dog, Cow, Pig, Horse, Chicken
Curated Selection
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