GAS 6 Polyclonal Antibody, PE-Cy5 Conjugated

Product Specifications

Background

Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

Synonyms

AXSF; AXLLG; Growth arrest-specific protein 6; GAS-6; AXL receptor tyrosine kinase ligand; GAS6

Gene ID

2621

Swiss Prot

Q14393

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Human, Mouse

Immunogen

551-650/721

Target

GAS 6

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE-Cy5

Source

KLH conjugated synthetic peptide derived from human GAS 6

Applications

Purification

Purified by Protein A.

Excitation Emission

488nm/670nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2621

Predicted Cross Reactivity

Rat, Dog, Cow, Pig, Horse, Chicken

Curated Selection

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