PGC1 beta Polyclonal Antibody, PE Conjugated
Product Specifications
Background
Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure.Tissue specificity: Ubiquitous with higher expression in heart, brain and skeletal muscle.
Synonyms
PERC; peroxisome prolerative activated receptor, gamma, coactivator 1, ; peroxisome prolerator-activated receptor gamma coactivator 1 beta; Peroxisome prolerator-activated receptor gamma coactivator 1-beta; peroxisome prolerator-activated receptor gamma, coactivator 1 beta; PGC-1beta; PGC-1-beta; PGC-1-related estrogen receptor alpha coactivator; PGC1; PPAR gamma coactivator-1beta; PPAR-gamma coactivator 1-beta; PPARGC-1-beta; PPARGC1; Ppargc1b; PRGC2_HUMAN.
Gene ID
133522
Cellular Locus
Nucleus
Host
Rabbit
Immunogen
901-1023/1023
Target
PGC1 beta
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human PGC1 beta
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
133522
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Pig, Rabbit, GuineaPig
Curated Selection
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