Phospho-Smad2 (Ser250) Polyclonal Antibody, AbBy Fluor™ 647 Conjugated
Product Specifications
Background
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma.
Synonyms
Smad2 (phospho S250) ; p-Smad2 (phospho S250) ; hMAD 2; hMAD 3; hSMAD2; hSMAD3; Mad related protein 2; MADH2; MADH3; MADR2; Mothers against DPP homolog 2; Mothers against DPP homolog 3; Sma and Mad related protein 2; SMA and MAD related protein 3; SMAD 2; SMAD 3; SMAD family member 2; SMAD family member 3.
Gene ID
4087
Swiss Prot
Q15796
Modification Site
Ser250
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
Phospho-Smad2 (Ser250)
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 647
Source
KLH conjugated synthesised phosphopeptide derived from human Smad2 around the phosphorylation site of Ser250
Applications
WB, FCM
Purification
Purified by Protein A.
Excitation Emission
650nm/665nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
4087
Predicted Cross Reactivity
Rat, Dog, Cow, Pig
More Discoveries
Explore Other Products
Browse additional items from our catalog
FAB8399RF 0.1 mL
Mouse Monoclonal CXCR7/RDC-1 Antibody (896032R) [FITC]
Sign In for Pricing
View Details 
034189-FITC 200 µL
CPT1C, CT (CPT1C, CATL1, Carnitine O-palmitoyltransferase 1, brain isoform, CPT IC, Carnitine O-palmitoyltransferase I, brain isoform, Carnitine palmitoyltransferase 1C) (FITC) discontinued
Sign In for Pricing
View Details 47040151 3x 1.0 µg DNA
TMEM31 CRISPR All-in-one AAV vector set (with saCas9)(Human)
Sign In for Pricing
View Details 
EK342257 96 Well
Rat ECF/CCL11 (Eosinophil Chemotactic Factor) ValidElisa Kit
Sign In for Pricing
View Details