Histone H3 (acetyl K27) Polyclonal Antibody, APC-Cy5.5 Conjugated
Product Specifications
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms
Acetyl H3; Histone H3 (acetyl k27) ; H3K27; H 3; H3 3 Like Sequence MH921; H3 3A; H3; H3 Histone; H3 Histone Family Member E Pseudogene; H3.4; H3/A; H3/g; H31_HUMAN; H3F3; H3FA; H3FT; H3t; HIST1H3J; HIST3H3; Histone cluster 1, H3a; Histone H3 3 Pseudogene; Histone H3.1; Histone H3.3; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l
Gene ID
8290
Swiss Prot
P68431
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Rat
Target
Histone H3 (acetyl K27)
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy5.5
Source
KLH conjugated Synthesised acetylpeptide derived from human Histone H3 around the acetylation site of K27
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/694nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
8290
Curated Selection
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