Histone H3 (acetyl K27) Polyclonal Antibody, APC Conjugated
Product Specifications
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms
Acetyl H3; Histone H3 (acetyl k27) ; H3K27; H 3; H3 3 Like Sequence MH921; H3 3A; H3; H3 Histone; H3 Histone Family Member E Pseudogene; H3.4; H3/A; H3/g; H31_HUMAN; H3F3; H3FA; H3FT; H3t; HIST1H3J; HIST3H3; Histone cluster 1, H3a; Histone H3 3 Pseudogene; Histone H3.1; Histone H3.3; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l
Gene ID
8290
Swiss Prot
P68431
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Rat
Target
Histone H3 (acetyl K27)
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated Synthesised acetylpeptide derived from human Histone H3 around the acetylation site of K27
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
8290
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