FEM 1B Polyclonal Antibody, Cy3 Conjugated

Product Specifications

Background

Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.

Synonyms

F1AA; F1A-ALPHA; FEM1-beta; Protein fem-1 homolog B; FEM1b; Fem-1-like death receptor-binding protein alpha; Fem-1-like in apoptotic pathway protein alpha; KIAA0396

Gene ID

10116

Swiss Prot

Q9UK73

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Rat

Immunogen

531-627/627

Target

FEM 1B

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human FEM 1B

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

10116

Predicted Cross Reactivity

Human, Mouse, Cow, Sheep, Horse, Chicken, Rabbit

Curated Selection

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