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FEM 1B Polyclonal Antibody, Biotin Conjugated

Product Specifications

Background

Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.

Synonyms

F1AA; F1A-ALPHA; FEM1-beta; Protein fem-1 homolog B; FEM1b; Fem-1-like death receptor-binding protein alpha; Fem-1-like in apoptotic pathway protein alpha; KIAA0396

Gene ID

10116

Swiss Prot

Q9UK73

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Rat

Immunogen

531-627/627

Target

FEM 1B

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human FEM 1B

Applications

ELISA, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

10116

Predicted Cross Reactivity

Human, Mouse, Cow, Sheep, Horse, Chicken, Rabbit

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