Glucokinase regulatory protein Antibody, PE Conjugated
Product Specifications
Background
Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.
Synonyms
GKRP; FGQTL5; Glucokinase regulatory protein; Glucokinase regulator; GCKR
Gene ID
2646
Swiss Prot
Q14397
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Rat
Immunogen
121-220/625
Target
Glucokinase regulatory protein
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human GCKR
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
2646
Predicted Cross Reactivity
Human, Mouse, Dog, Pig, Horse, Rabbit
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