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Glucokinase regulatory protein Antibody, Cy3 Conjugated

Product Specifications

Background

Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.

Synonyms

GKRP; FGQTL5; Glucokinase regulatory protein; Glucokinase regulator; GCKR

Gene ID

2646

Swiss Prot

Q14397

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Rat

Immunogen

121-220/625

Target

Glucokinase regulatory protein

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human GCKR

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2646

Predicted Cross Reactivity

Human, Mouse, Dog, Pig, Horse, Rabbit

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