Glucokinase regulatory protein Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.
Synonyms
GKRP; FGQTL5; Glucokinase regulatory protein; Glucokinase regulator; GCKR
Gene ID
2646
Swiss Prot
Q14397
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Rat
Immunogen
121-220/625
Target
Glucokinase regulatory protein
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from human GCKR
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
2646
Predicted Cross Reactivity
Human, Mouse, Dog, Pig, Horse, Rabbit
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