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Glucokinase regulatory protein Antibody, AbBy Fluor™ 405 Conjugated

Product Specifications

Background

Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.

Synonyms

GKRP; FGQTL5; Glucokinase regulatory protein; Glucokinase regulator; GCKR

Gene ID

2646

Swiss Prot

Q14397

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Rat

Immunogen

121-220/625

Target

Glucokinase regulatory protein

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 405

Source

KLH conjugated synthetic peptide derived from human GCKR

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

401nm/421nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2646

Predicted Cross Reactivity

Human, Mouse, Dog, Pig, Horse, Rabbit

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