Glucokinase regulatory protein Antibody
Product Specifications
Background
Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.
Synonyms
GKRP; FGQTL5; Glucokinase regulatory protein; Glucokinase regulator; GCKR
Gene ID
2646
Swiss Prot
Q14397
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Rat
Immunogen
121-220/625
Target
Glucokinase regulatory protein
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human GCKR
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
2646
Predicted Cross Reactivity
Human, Mouse, Dog, Pig, Horse, Rabbit
Curated Selection
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