Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

GLMN Polyclonal Antibody, PerCP-Cy5.5 Conjugated

Product Specifications

Background

Isoform 1: Regulatory component of cullin-RING-based SCF (SKP1-Cullin-F-box protein) E3 ubiquitin-protein ligase complexes.) . Inhibits E3 ubiquitin ligase activity by binding to RBX1 (via RING domain) and inhibiting its interaction with the E2 ubiquitin-conjugating enzyme CDC34. Inhibits RBX1-mediated neddylation of CUL1. Required for normal stability and normal cellular levels of key components of SCF ubiquitin ligase complexes, including FBXW7, RBX1, CUL1, CUL2, CUL3, CUL4A, and thereby contributes to the regulation of CCNE1 and MYC levels (By similarity) . Essential for normal development of the vasculature. Contributes to the regulation of RPS6KB1 phosphorylation

Synonyms

FAP; GVM; GLML; FAP48; FAP68; FKBPAP; VMGLOM; Glomulin; FK506-binding protein-associated protein; FKBP-associated protein; GLMN; GLMN_HUMAN

Gene ID

11146

Swiss Prot

Q92990

Cellular Locus

Cytoplasm, Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

151-250/594

Target

GLMN

Clonality

Polyclonal

Isotype

IgG

Conjugation

PerCP-Cy5.5

Source

KLH conjugated synthetic peptide derived from human FK506 binding protein associated protein

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

482nm/694nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

11146

Predicted Cross Reactivity

Mouse, Rat, Dog, Pig, Horse

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Rabbit Monoclonal KLF12 Antibody (1230C) [Janelia Fluor 669]
FAB9097JF669 0.1 mL

Rabbit Monoclonal KLF12 Antibody (1230C) [Janelia Fluor 669]

Sign In for Pricing
View Details
EIF4AI (m) : 293T Lysate
sc-125292 100 µg - 200 µL

EIF4AI (m) : 293T Lysate

Sign In for Pricing
View Details
Human PCED1B knockout cell line
ABC-KH11248 1 Vial

Human PCED1B knockout cell line

Sign In for Pricing
View Details
IL4I1 (NM_152899) Human Recombinant Protein
PH32767M2 50 µg

IL4I1 (NM_152899) Human Recombinant Protein

Sign In for Pricing
View Details
BEND6 (NM_152731) Human Recombinant Protein
PROTQ5SZJ8 20 µg

BEND6 (NM_152731) Human Recombinant Protein

Sign In for Pricing
View Details
GPR85 Polyclonal Antibody, Cy3 Conjugated
bs-15364R-Cy3 100 µL

GPR85 Polyclonal Antibody, Cy3 Conjugated

Sign In for Pricing
View Details