GLMN Polyclonal Antibody, FITC Conjugated

Product Specifications

Background

Isoform 1: Regulatory component of cullin-RING-based SCF (SKP1-Cullin-F-box protein) E3 ubiquitin-protein ligase complexes.) . Inhibits E3 ubiquitin ligase activity by binding to RBX1 (via RING domain) and inhibiting its interaction with the E2 ubiquitin-conjugating enzyme CDC34. Inhibits RBX1-mediated neddylation of CUL1. Required for normal stability and normal cellular levels of key components of SCF ubiquitin ligase complexes, including FBXW7, RBX1, CUL1, CUL2, CUL3, CUL4A, and thereby contributes to the regulation of CCNE1 and MYC levels (By similarity) . Essential for normal development of the vasculature. Contributes to the regulation of RPS6KB1 phosphorylation

Synonyms

FAP; GVM; GLML; FAP48; FAP68; FKBPAP; VMGLOM; Glomulin; FK506-binding protein-associated protein; FKBP-associated protein; GLMN; GLMN_HUMAN

Gene ID

11146

Swiss Prot

Q92990

Cellular Locus

Cytoplasm, Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

151-250/594

Target

GLMN

Clonality

Polyclonal

Isotype

IgG

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human FK506 binding protein associated protein

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

11146

Predicted Cross Reactivity

Mouse, Rat, Dog, Pig, Horse

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

SR508135 1 Kit

Cntn4 Rat siRNA Oligo Duplex (Locus ID 116658)

Ask

View Details

RR214182L4 10 µg

Bcl2 (NM_016993) Rat Tagged Lenti ORF Clone

Ask

View Details

LS006512-100ug 100 µg

SLC1A7 (NM_006671) Human Over-expression Lysate

Ask

View Details

SI018342B 1 Each

Human XRCC4 Pre-designed siRNA Set B

Ask

View Details

MF-0071936-01 20 µL

Anti-Carboxypeptidase B1 Antibody (2S669)

Ask

View Details

MF-0071936-02 100 µL

Anti-Carboxypeptidase B1 Antibody (2S669)

Ask

View Details