Vesicular GABA transporter (VGAT) Antibody

Product Specifications

Background

The Vesicular GABA Amino Acid Transporter (VGAT) is responsible for transport of the inhibitory neurotransmitter into synaptic vesicles (McIntire et al., 1997) . The VGAT protein (also known as the Vesicular Inhibitory Amino Aid Transporter or VIAAT) is expressed in synaptic vesicles of both glycine and GABAergic synapses throughout the CNS (Chaudhry et al., 1998) . Expression of the VGAT protein changes during development and also in response to patterns of neuronal activity (De et al., 2005) .

Synonyms

BA122O1.1 antibody, GABA and glycine transporter antibody, hVIAAT antibody, SLC32A1 antibody, SLC32A 1 antibody, Slc32a1 antibody, solute carrier family 32 (GABA vesicular transporter) member 1 antibody, Solute carrier family 32 member 1 antibody, Vesicular GABA Amino Acid Transporter antibody, Vesicular GABA transporter antibody, Vesicular inhibitory amino acid transporter antibody, VGAT antibody, VIAAT antibody, VIAAT_HUMAN antibody

Gene ID

83612

Swiss Prot

O35458

Host

Rabbit

Cross Reactivity

Mouse, Rat, Chicken, Xenopus

Target

Vesicular GABA transporter (VGAT)

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat VGAT, conjugated to keyhole limpet hemocyanin (KLH) .

Applications

WB, IHC

Purification

Antigen Affinity purification from Pooled whole antiserum

Concentration

Lot Dependent

Dilution

WB (1:300-5000), IHC ()

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Modification

Unmodified

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.