Tau Antibody
Product Specifications
Background
Tau is a key microtubule-associated protein that plays an important role in the formation of microtubules in axons (Binder et al. 1985) . Six tau isoforms have been identified as products of a single gene produced by alternative mRNA splicing (Goedert 1990) . Tau mutations have been implicated in many neurodegenerative disorders such as Alzheimer’s disease (AD), Pick’s disease and progressive supranuclear palsy.
Synonyms
AI413597 antibody, AW045860 antibody, DDPAC antibody, FLJ31424 antibody, FTDP 17 antibody, G protein beta1/gamma2 subunit interacting factor 1 antibody, MAPT antibody, MAPTL antibody, MGC134287 antibody, MGC138549 antibody, MGC156663 antibody, Microtubule associated protein tau antibody, Microtubule associated protein tau isoform 4 antibody, Microtubule-associated protein tau antibody, MSTD antibody, Mtapt antibody, MTBT1 antibody, MTBT2 antibody, Neurofibrillary tangle protein antibody, Paired helical filament tau antibody, Paired helical filament-tau antibody, PHF tau antibody, PHF-tau antibody, PPND antibody, PPP1R103 antibody, Protein phosphatase 1 regulatory subunit 103 antibody, pTau antibody, RNPTAU antibody, TAU antibody, TAU_HUMAN antibody, Tauopathy and respiratory failure included antibody
Gene ID
4137
Swiss Prot
P10636
Host
Chicken
Cross Reactivity
Human, Mouse, Rat, Bovine, Pig
Target
Tau
Clonality
Polyclonal
Isotype
IgY
Conjugation
Unconjugated
Source
Recombinant full length human tau expressed in and purified from E.Coli.
Applications
WB, IHC
Purification
Total IgY fraction
Concentration
Lot Dependent
Dilution
WB (1:300-5000), IHC ()
Buffer
PBS + 10 mM NaN3.
Modification
Unmodified
Storage Conditions
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
Specificity
Specific for the ~48, 65 & 75 kDa tau isoforms.
Gene ID URL
4137
Frequently Asked Questions
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