Ribosomal S6 kinase 2 Antibody

Product Specifications

Background

The p90 ribosomal S6 kinases (RSK) 1–4 are downstream members of the extracellular signal-regulated kinase (ERK) /MAPK cascade. The loss of RSK2 activity in humans leads to Coffin–Lowry syndrome, which is characterized by mental retardation and growth deficits (Hanauer and Young, 2002) . Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling (Sheffler et al., 2006) .

Synonyms

90 kDa ribosomal protein S6 kinase 2 antibody, HU 2 antibody, KS6A2_HUMAN antibody, MAP kinase activated protein kinase 1c antibody, MAP kinase-activated protein kinase 1c antibody, MAPK-activated protein kinase 1c antibody, MAPKAP kinase 1c antibody, MAPKAPK-1c antibody, MAPKAPK1C antibody, Mitogen.activated protein kinase-activated protein kinase 1C antibody, p90 RSK3 antibody, p90-RSK 2 antibody, p90RSK2 antibody, pp90RSK3 antibody, Ribosomal protein S6 kinase alpha-2 antibody, ribosomal protein S6 kinase 90kDa polypeptide 2 antibody, Ribosomal S6 kinase 3 antibody, RPS6KA2 antibody, RSK3 antibody, RSK 3 antibody, RSK antibody, RSK-3 antibody, S6K alpha antibody, S6K alpha 2 antibody, S6K-alpha-2 antibody

Gene ID

20112

Swiss Prot

Q9WUT3

Host

Rabbit

Cross Reactivity

Human

Target

Ribosomal S6 kinase 2

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

Synthetic peptide corresponding to amino acid residues from the C-terminal region on mouse ribosomal S6 kinase 2, conjugated to keyhole limpet hemocyanin (KLH) .

Applications

Purification

Antigen Affinity purification from Pooled whole antiserum

Concentration

Lot Dependent

Dilution

WB (1:300-5000)

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Modification

Unmodified

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.