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RBPMS Antibody

Product Specifications

Background

RBPMS (RNA binding protein with multiple splicing), also known as HERMES, contains one RRM (RNA recognition motif) domain and belongs to the RRM family of RNA-binding proteins. RBPMS exists as multiple alternatively spliced isoforms and is thought to bind RNA, possibly playing a role in RNA-related events, such as transcription and translation. RNA-binding proteins that are specific to retinal ganglion cells (RGCs) have been previously identified as excellent markers for RGCs (Kwong et al., 2010) . Recent findings show that antibodies against RBPMS are robust reagents that exclusively identify RGCs in multiple mammalian species (Rodriguez et al. 2014)

Synonyms

FLJ32971 antibody, Heart and RRM expressed sequence antibody, Hermes antibody, RBP MS antibody, RBP-MS antibody, Rbpms antibody, RBPMS_HUMAN antibody, RNA binding protein gene with multiple splicing antibody, RNA-binding protein with multiple splicing antibody

Gene ID

19663

Swiss Prot

Q9WVB0

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat, Pig, Rabbit, Guinea Pig, Zebrafish, Cat, Non-Human Primate, Tree Shrew, Whale

Target

RBPMS

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat RBPMS, conjugated to keyhole limpet hemocyanin (KLH) .

Applications

WB, IHC

Purification

Antigen Affinity purification

Concentration

Lot Dependent

Dilution

WB (1:300-5000), IHC ()

Buffer

PBS + 0.03% NaN3

Modification

Unmodified

Storage Conditions

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Specificity

Specific for endogenous levels of the ~24 kDa RBPMS protein.

Gene ID URL

19663

Predicted Cross Reactivity

Dog, Hamster

Curated Selection

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