Interferon alpha 11 Polyclonal Antibody, RBITC Conjugated
Product Specifications
Background
Interferons (IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites or tumor cells. They belong to the large class of glycoproteins known as cytokines. IFNs stimulate the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs can activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes; and they also increase the ability of uninfected host cells to resist new infection by virus. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon is produced by mitogen- or antigen-stimulated T lymphocytes.
Synonyms
IFNA; IFN-a; IFN-_; Interferon alpha; Interferon-alpha; IFNA1; IFNA2; IFNA5; IFNA6; IFNA8/6; IFNA7; IFNA9; IFNA11; IFNA12; IFNA13; IFNA15; IFNA16; IFNA6T; IFNAB; IFNA4; Pan Interferon alpha; IFNA13; IFNA1/13; IFNA7; IFNA10; IFNA14; IFNA17; IFNA21; IFNA8.
Gene ID
15962
Swiss Prot
P01572
Cellular Locus
Secreted
Host
Rabbit
Immunogen
101-190/190
Target
Interferon alpha 11
Clonality
Polyclonal
Isotype
IgG
Conjugation
RBITC
Source
KLH conjugated synthetic peptide derived from Mouse IFNA1
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
570nm/595nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Specificity
This antibody will detect all Human and Mouse Interferon alpha subtypes
Gene ID URL
15962
Predicted Cross Reactivity
Mouse, Rat
Curated Selection
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