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Interferon alpha 11 Polyclonal Antibody, PE Conjugated

Product Specifications

Background

Interferons (IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites or tumor cells. They belong to the large class of glycoproteins known as cytokines. IFNs stimulate the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs can activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes; and they also increase the ability of uninfected host cells to resist new infection by virus. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon is produced by mitogen- or antigen-stimulated T lymphocytes.

Synonyms

IFNA; IFN-a; IFN-_; Interferon alpha; Interferon-alpha; IFNA1; IFNA2; IFNA5; IFNA6; IFNA8/6; IFNA7; IFNA9; IFNA11; IFNA12; IFNA13; IFNA15; IFNA16; IFNA6T; IFNAB; IFNA4; Pan Interferon alpha; IFNA13; IFNA1/13; IFNA7; IFNA10; IFNA14; IFNA17; IFNA21; IFNA8.

Gene ID

15962

Swiss Prot

P01572

Cellular Locus

Secreted

Host

Rabbit

Immunogen

101-190/190

Target

Interferon alpha 11

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE

Source

KLH conjugated synthetic peptide derived from Mouse IFNA1

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

This antibody will detect all Human and Mouse Interferon alpha subtypes

Gene ID URL

15962

Predicted Cross Reactivity

Mouse, Rat

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