Rab 3 Antibody

Product Specifications

Background

Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D (Schluter et al., 2004) . These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters (Coppola et al., 2002) . Specifically, Rab3’s are thought to play a key role in presynaptic vesicle trafficking and priming (Schluter et al., 2006) .

Synonyms

Rab 3A antibody, RAB 3A member RAS oncogene family antibody, Rab3a antibody, RAB3A member RAS oncogene family antibody, RAB3A_HUMAN antibody, RAS associated protein RAB 3A antibody, RAS associated protein RAB3A antibody, Ras related protein Rab 3A antibody, Ras related protein Rab3A antibody, Ras-related protein Rab-3A antibody

Gene ID

25531

Swiss Prot

P63012

Host

Rabbit

Cross Reactivity

Rat

Target

Rab 3

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat Rab 3, conjugated to keyhole limpet hemocyanin (KLH) .

Applications

Purification

Antigen Affinity purification from Pooled whole antiserum

Concentration

Lot Dependent

Dilution

WB (1:300-5000)

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Modification

Unmodified

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.