Rab 3 Antibody
Product Specifications
Background
Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D (Schluter et al., 2004) . These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters (Coppola et al., 2002) . Specifically, Rab3’s are thought to play a key role in presynaptic vesicle trafficking and priming (Schluter et al., 2006) .
Synonyms
Rab 3A antibody, RAB 3A member RAS oncogene family antibody, Rab3a antibody, RAB3A member RAS oncogene family antibody, RAB3A_HUMAN antibody, RAS associated protein RAB 3A antibody, RAS associated protein RAB3A antibody, Ras related protein Rab 3A antibody, Ras related protein Rab3A antibody, Ras-related protein Rab-3A antibody
Gene ID
25531
Swiss Prot
P63012
Host
Rabbit
Cross Reactivity
Rat
Target
Rab 3
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat Rab 3, conjugated to keyhole limpet hemocyanin (KLH) .
Applications
WB
Purification
Antigen Affinity purification from Pooled whole antiserum
Concentration
Lot Dependent
Dilution
WB (1:300-5000)
Buffer
10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Modification
Unmodified
Storage Conditions
Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
Specificity
Specific for endogenous levels of the ~27 kDa Rab3 protein.
Gene ID URL
25531
Predicted Cross Reactivity
Human, Mouse, Xenopus, Non-Human Primate
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