PSD-95 Antibody

Product Specifications

Background

PSD-95 is a very prominent component of the postsynaptic densities of synapses. It contains three PDZ domains which play key roles in its interactions with other proteins in the synapse. It has been proposed that these PDZ domains organize glutamate receptors and their associated signaling proteins and determine the size and strength of synapses (Kim and Sheng, 2004) . Recent work suggests that interaction of the NMDAR with PSD-95 via these PDZ domains can be regulated by phosphorylation (Chung et al., 2004) .

Synonyms

Discs large homolog 4 antibody, Disks large homolog 4 antibody, DLG 4 antibody, Dlg4 antibody, DLG4_HUMAN antibody, FLJ97752 antibody, FLJ98574 antibody, Human post synaptic density protein 95 antibody, Post synaptic density protein 95 antibody, Postsynaptic density protein 95 antibody, PSD 95 antibody, PSD-95 antibody, PSD95 antibody, SAP 90 antibody, SAP-90 antibody, SAP90 antibody, Synapse associated protein 90 antibody, Synapse-associated protein 90 antibody, Tax interaction protein 15 antibody

Gene ID

29495

Swiss Prot

P31016

Host

Rabbit

Cross Reactivity

Mouse, Rat

Target

PSD-95

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat PSD-95, conjugated to keyhole limpet hemocyanin (KLH) .

Applications

Purification

Antigen Affinity purification from Pooled whole antiserum

Concentration

Lot Dependent

Dilution

WB (1:300-5000)

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Modification

Unmodified

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.