Potassium Channel, Voltage-Gated, Kv3.1 Subunit (Ser503) Antibody

Voltage-gated K+ channels are important determinants of neuronal membrane excitability. Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types (Maletic-Savatic et al., 1995; Pongs, 1999; Blaine and Ribera, 1998; Burger and Ribera, 1996) . The Kv3.1 potassium channel is expressed at high levels in neurons that characteristically fire rapid trains of action potentials (Gan et al., 1999) . Particularly high levels of this channel are found in neurons of the auditory brainstem. These neurons appear to participate in neural circuits that determine the intensity and timing of auditory stimuli and use this information to determine the location of sounds in space (von Hehn et al., 2004) .

C230009H10Rik antibody, FLJ41162 antibody, FLJ42249 antibody, FLJ43491 antibody, Kcnc1 antibody, KCNC1 antibody, KCNC1_HUMAN antibody, Kcr2 1 antibody, KShIIIB antibody, Kv3.1 antibody, Kv4 antibody, MGC129855 antibody, NGK2 antibody, Potassium voltage-gated channel subfamily C member 1 antibody, Shaw antibody, Voltage gated potassium channel antibody, Voltage gated potassium channel subunit Kv3.1 antibody, Voltage-gated potassium channel subunit Kv3.1 antibody, Voltage-gated potassium channel subunit Kv4 antibody

The antigen is a phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser503 of the rat voltage-gated potassium channel Kv3.1, conjugated to keyhole limpet hemocyanin (KLH) .