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NSF (N-ethylmaleimide sensitive fusion protein) Antibody

Product Specifications

Background

NSF (N-ethylmaleimide sensitive fusion protein) is a critical component of the SNARE (soluble NSF attachment protein receptors) protein complex that is involved in synaptic vesicle trafficking. Specifically, NSF has been found to be essential in membrane fusion. Furthermore, NSF has been recently demonstrated to bind other protein complexes such as AMPA receptor subunits (GluR2), GATE-16, LMA-1 and Rabs suggesting a more diverse role in the assembly of various protein complexes (Whiteheart et al., 2004) .

Synonyms

N ethylmaleimide sensitive factor antibody, N ethylmaleimide sensitive factor like protein antibody, N ethylmaleimide sensitive fusion protein antibody, N-ethylmaleimide-sensitive fusion protein antibody, NEM sensitive fusion protein antibody, NEM-sensitive fusion protein antibody, NSF antibody, NSF_HUMAN antibody, SKD 2 antibody, SKD2 antibody, Vesicle fusing ATPase antibody, Vesicle-fusing ATPase antibody, Vesicular fusion protein NSF antibody, Vesicular-fusion protein NSF antibody

Gene ID

60355

Swiss Prot

Q9QUL6

Host

Rabbit

Cross Reactivity

Rat

Target

NSF (N-ethylmaleimide sensitive fusion protein)

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat NSF, conjugated to keyhole limpet hemocyanin (KLH) .

Applications

WB

Purification

Antigen Affinity purification from Pooled whole antiserum

Concentration

Lot Dependent

Dilution

WB (1:300-5000)

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Modification

Unmodified

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Specificity

Specific for endogenous levels of the ~75 kDa NSF protein.

Gene ID URL

60355

Predicted Cross Reactivity

Human, Non-Human Primate

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