SAP62 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.
Synonyms
PRP11; SAP62; PRPF11; SF3a66; Splicing factor 3A subunit 2; Spliceosome-associated protein 62; SAP 62; SF3A2
Gene ID
8175
Swiss Prot
Q15428
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
65-160/464
Target
SAP62
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from human SAP62
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
8175
Predicted Cross Reactivity
Human, Rat, Dog, Cow, Chicken
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