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SAP62 Polyclonal Antibody, AbBy Fluor™ 405 Conjugated

Product Specifications

Background

Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.

Synonyms

PRP11; SAP62; PRPF11; SF3a66; Splicing factor 3A subunit 2; Spliceosome-associated protein 62; SAP 62; SF3A2

Gene ID

8175

Swiss Prot

Q15428

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

65-160/464

Target

SAP62

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 405

Source

KLH conjugated synthetic peptide derived from human SAP62

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

401nm/421nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

8175

Predicted Cross Reactivity

Human, Rat, Dog, Cow, Chicken

Curated Selection

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