Phospholipase C beta 1 Antibody, FITC Conjugated

Product Specifications

Background

Phospholipase C beta 1 catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. Its gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for its gene.

Synonyms

1-phosphatidylinositol-45-bisphosphate phosphodiesterase beta 1; 1vphosphatidylinositol 4,5 bisphosphate phosphodiesterase beta 1 ; Phosphb; Phosphoinositide phospholipase C; Phosphoinositide phospholipase C-beta 1; Phospholipase C beta 1 phosphoinositide-specic; Phospholipase C I; PI PLC; PLC 1; PLC_1; PLC-154; PLC-beta-1; PLC-I; PLC154; Plcb; PLCB1; Plcb1 protein; PLCbeta1.

Gene ID

23236

Cellular Locus

Cytoplasm, Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

441-540/1216

Target

Phospholipase C beta 1

Clonality

Polyclonal

Isotype

IgG

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human Phospholipase C beta 1

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

23236

Predicted Cross Reactivity

Mouse, Dog, Cow, Horse, Chicken

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